Critical Care and Emergency Medicine

Acid-Base Disturbances 

• Acid-Base Disturbances: A Key Concept to Prevent Life-Threatening State of Sick Children. (Acta Scientific Paediatrics 2020)
• Acid-Base Disorders. (Pediatr Rev. 2016) 
• Paediatric acid-base disorders: A case-based review of procedures and pitfalls. (Paediatr Child Health. 2013) 
• Acid–Base and Electrolyte Disturbances. NEJM Resident 360

Acute Respiratory Diseases

• Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference. (Pediatr Crit Care Med. 2023) 
• The Current State of Pediatric Acute Respiratory Distress Syndrome. (Pediatr Allergy Immunol Pulmonol. 2019)

Burns

• Update on the management of burns in paediatrics. (BJA Educ. 2020)
• Burn Care for Children. (Pediatr Rev 2018)
• Critical Burns. NEJM Resident 360

Critical Care Management 

• Select topics in the management of critically ill children (AJHP 2019)

ECMO

• Sedative and Analgesic Pharmacokinetics During Pediatric ECMO. (J Pediatr Pharmacol Ther. 2020)
• Drugs pharmacokinetics during veno-venous extracorporeal membrane oxygenation in pediatrics. (J Thorac Dis. 2018)
• Pediatric cardiovascular drug dosing in critically ill children and extracorporeal membrane oxygenation. (J Cardiovasc Pharmacol. 2011)
• Anticoagulation Therapy during Extracorporeal Membrane Oxygenator Support in Pediatric Patients. (Chonnam Med J. 2017)
• Thromboprophylaxis in extracorporeal circuits:  current pharmacological strategies and future directions. (Am J Cardiovasc Drugs. 2017)
• An overview of medical ECMO for neonates. (InSeminars in perinatology 2018)
• Pediatric Extracorporeal Membrane Oxygenation. (Crit Care Clin. 2017)

Emergency Preparedness

• Practice Parameter on Disaster Preparedness (J. Am. Acad. Child Adolesc. Psychiatry, 2013)
• Emergency Preparedness
• National Pediatric Readiness Project
• Pediatric Preparedness Resource Kit
• Children In Disasters: Health Professionals

Fluid and Electrolyte Disorders

• Syndrome of inappropriate antidiuretic hormone secretion and cerebral/renal salt wasting syndrome: similarities and differences. (Front Pediatr. 2014).
• Syndrome of Inappropriate Secretion of Antidiuretic Hormone and Hyponatremia. (Pediatr Rev 2018)  
• Diabetes Insipidus. (Pediatr Rev 2020)

Hyperglycemia of Critical Illness

• Tight glycemic control in critically ill pediatric patients: a systematic review and meta-analysis. (Crit Care. 2018)
• Stress Hyperglycemia in Pediatric Critical Illness: The Intensive Care Unit Adds to the Stress! (J Diabetes Sci Technol. 2012)
• Medication-induced hyperglycemia: pediatric perspective. (BMJ Open Diabetes Res Care. 2020)

Near Drowning

• Drowning. (N Engl J Med. 2012) 
• Prevention of Drowning. (Pediatrics 2021) 
• Epidemiology, clinical aspects, and management of pediatric drowning. (Ital J Pediatr. 2023) 

Organ Donor Management 

• Pediatric Organ Donation and Transplantation: Across the Care Continuum. Pediatrics. 2023 Aug 1;152(2):e2023062923.
• Management of the Pediatric Organ Donor. J Pediatr Pharmacol Ther. 2019 Jul-Aug; 24(4): 276–289.

PALS

• Part 4: Pediatric Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. (Circulation. 2020) 

PK/PD Alterations in Critical Care

• Pharmacokinetics and Pharmacodynamics in the Critically Ill Child. (Pediatr Clin North Am. 2008)
• Clinical Pharmacology Studies in Critically Ill Children. (Pharm Res. 2017)
• Personalized application of antimicrobial drugs in pediatric patients with augmented renal clearance: a review of literature. (Eur J Pediatr. 2023)

Sedation, Analgesia and Neuromuscular Blockade

• 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility. (Pediatric Critical Care Medicine 2022) 
• Practical approaches to sedation and analgesia in the newborn. (Journal of Perinatology 2021) 

Procedural Sedation

• Procedural Sedation and Analgesia in the Pediatric Emergency Department: A Review of sedative pharmacology (Pediatr Rev. 2017)
• Pediatric Sedation Management. (Pediatr Rev. 2016)
• Procedural Sedation and Analgesia in pediatric patients. (J Pediatr Neurosci 2014)
• An Introduction to the Smart Tots Concensus Statement on the Use of Anesthetic and Sedative Drugs in Infants and Toddlers.  (J Perianesth Nurs. 2016)

Iatrogenic withdrawal syndrome (IWS)

• The Withdrawal Assessment Tool-1 (WAT-1): an assessment instrument for monitoring opioid and benzodiazepine withdrawal symptoms in pediatric patients. (Pediatr Crit Care Med 2008)
• Recognition and Management of Iatrogenically Induced Opioid Dependence and Withdrawal in Children. (Pediatrics 2014)
• Tolerance and Withdrawal From Prolonged Opioid Use in Critically Ill Children (Pediatrics 2010)

Rapid Sequence Intubation

• Guidelines for monitoring and management of pediatric patients before, during, and after sedation for diagnostic and therapeutic procedures: update 2016 (Pediatrics 2016)
• Effectiveness of interventions to improve medication use during rapid-sequence intubation in a pediatric emergency department.( AJHP 2017)
• Pharmacotherapy optimization for rapid sequence intubation in the emergency department. (Am J Emerg Med. 2023)

Shock (cardiogenic, septic)

Cardiogenic

• Cardiogenic Shock. (The Open Pediatric Medicine Journal 2013)
• Cardiogenic shock. (Pediatr Rev. 2015) 

Septic

• Surviving Sepsis Campaign international guidelines of the management of septic shock and sepsis-associated organ dysfunction in children.(Pediatr Crit Care Med. 2020).
• American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock. (Crit Care Med. 2017)
• Pediatric sepsis: Important considerations for diagnosing and managing severe infections in infants, children, and adolescents. (Virulence 2014) 
• Pediatric sepsis.(Current Opinion in Pediatrics June 2016)

Sleep Management 

• Pediatric Intensive Care Unit related Sleep and Circadian Dysregulation: a focused review. (Semin Pediatr Neurol. 2023)
• Ensuring Safe Sleep in the Pediatric Intensive Care Unit: A Systematic Review of Informed Development of Clinical Guidelines for Implementation in Practice. (Pediatr Health Care. 2023)

Status Asthmaticus

• Guidelines for the Diagnosis and Management of Asthma. (NHLBI and NAEPP 2007)
• Severe Acute Asthma Exacerbation in Children: A Stepwise Approach for Escalating Therapy in a Pediatric Intensive Care Unit. (J Pediatr Pharmacol Ther. 2013) 
• GINA. (Main Report: 2022 GINA Report, Global Strategy for Asthma Management and Prevention: 2020)

Toxicology

• Pediatric Toxicology. Quick Hits for Pediatric Emergency 
• Pediatric Toxicology: Specialized Approach to the Poisoned Child. (Emerg Med Clin North Am. 2014)
• Pediatric Toxicology Update: Rational Management of Pediatric Exposures and Poisonings. Emergency Medicine Practice

Trauma

• Prophylaxis against venous thromboembolism in pediatric trauma: A practice management guideline from the Eastern Association for the Surgery of Trauma and the Pediatric Trauma Society. (J Trauma Acute Care Surg. 2017).
• Management of Pediatric Trauma.(Pediatrics 2016)  
• Pediatric Trauma Society Guidelines HUB

Traumatic Brain Injury

• Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies. (Pediatric Critical Care Medicine 2019) 
• Guidelines for the Management of Severe Traumatic Brain Injury, (Fourth Edition. Neurosurgery. 2017)
• Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children. (JAMA Pediatr. 2018) 
• Barbiturate coma treatment in children with refractory intracranial hypertension due to traumatic brain injury; is it useful? (J Neurosurg Pediatr. 2019)