6/11/2025

Ephedrine Injection

Products Affected - Description

- Emerphed injection, Nexus Pharmaceuticals, 5 mg/mL, 10 mL syringe, 10 count, NDC 14789-0251-10
- Emerphed injection, Nexus Pharmaceuticals, 5 mg/mL, 5 mL syringe, 10 count, NDC 14789-0252-10
- Ephedrine injection, Dr. Reddy's, 50 mg/mL, 1 mL vial, 25 count, NDC 43598-0735-25
- Ephedrine injection, Endo Pharmaceuticals, 5 mg/mL, 10 mL vial, 10 count, NDC 42023-0243-01
- Ephedrine injection, Endo Pharmaceuticals, 50 mg/mL, 1 mL vial, 25 count, NDC 42023-0216-25
- Ephedrine injection, Hikma, 5 mg/mL, 5 mL syringe, 10 count, NDC 00641-6236-10
- Ephedrine injection, Sagent, 50 mg/mL, 1 mL vial, 25 count, NDC 25021-0836-01

Reason for the Shortage

- Dr. Reddy's has ephedrine injection available.
- Endo did not provide a reason for the shortage.
- Exela has Avokaz injection available.
- Hikma did not provide a reason for the shortage.
- Nexus did not provide a reason for the shortage.
- Sagent did not provide a reason for the shortage.
- Sandoz has ephedrine injection available.
- Somerset has ephedrine injection available.

Available Products

- Akovaz injection, Exela Pharma Sciences, 5 mg/mL, 5 mL syringe, 10 count, NDC 51754-4250-03
- Akovaz injection, Exela Pharma Sciences, 50 mg/mL, 1 mL vial, 25 count, NDC 51754-4200-24
- Emerphed injection, Nexus Pharmaceuticals, 5 mg/mL, 10 mL vial, 10 count, NDC 14789-0250-10
- Ephedrine injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-6238-25
- Ephedrine injection, Sandoz, 50 mg/mL, 1 mL vial, 25 count, NDC 00781-3269-95
- Ephedrine injection, Somerset Therapeutics LLC, 50 mg/mL, 1 mL vial, 10 count, NDC 70069-0819-10

Estimated Resupply Dates

- Endo has ephedrine 5 mg/mL 1 mL and 10 mL vials on back order and the company estimates a release date of late-June 2025.
- Hikma has ephedrine 5 mg/mL 5 mL syringes on back order and the company cannot estimate a release date.
- Sagent has ephedrine 50 mg/mL 1 mL vials on back order and the company estimates a release date of June 2025.
- Nexus has Emerphed 5 mg/mL 5 mL and 10 mL syringes on back order and the company estimates a release date of mid- to late-July 2025.

Updated

Updated June 11, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. Created April 21, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

« Back to Drug Shortage Product Bulletins

Subscribe to AHFS Clinical Drug Information to get direct access to integrated drug shortages content, plus comprehensive and actionable drug information.