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11/13/2025

Leucovorin Calcium Tablets

Products Affected - Description

    • Leucovorin Calcium oral tablet, Hikma, 10 mg, bottle, 12 count, NDC 00054-4497-05
    • Leucovorin Calcium oral tablet, Hikma, 10 mg, bottle, 24 count, NDC 00054-4497-10
    • Leucovorin Calcium oral tablet, Hikma, 15 mg, bottle, 24 count, NDC 00054-4498-10
    • Leucovorin Calcium oral tablet, Hikma, 25 mg, bottle, 25 count, NDC 00054-4499-11
    • Leucovorin Calcium oral tablet, Hikma, 5 mg, bottle, 30 count, NDC 00054-4496-13
    • Leucovorin Calcium oral tablet, Hikma, 5 mg, bottle, 50 count, NDC 00054-8496-19
    • Leucovorin Calcium oral tablet, Ingenus Pharmaceuticals, 10 mg, bottle, 12 count, NDC 50742-0182-12
    • Leucovorin Calcium oral tablet, Ingenus Pharmaceuticals, 10 mg, bottle, 24 count, NDC 50742-0182-24
    • Leucovorin Calcium oral tablet, Ingenus Pharmaceuticals, 15 mg, bottle, 24 count, NDC 50742-0183-24
    • Leucovorin Calcium oral tablet, Ingenus Pharmaceuticals, 5 mg, bottle, 30 count, NDC 50742-0181-30
    • Leucovorin Calcium oral tablet, Ingenus Pharmaceuticals, 5 mg, bottle, 100 count, NDC 50742-0181-01
    • Leucovorin Calcium oral tablet, Leading, 10 mg, bottle, 12 count, NDC 69315-0185-12
    • Leucovorin Calcium oral tablet, Leading, 10 mg, bottle, 24 count, NDC 69315-0185-24
    • Leucovorin Calcium oral tablet, Leading, 15 mg, bottle, 24 count, NDC 69315-0186-24
    • Leucovorin Calcium oral tablet, Leading, 25 mg, bottle, 25 count, NDC 69315-0187-25
    • Leucovorin Calcium oral tablet, Leading, 5 mg, bottle, 30 count, NDC 69315-0184-03
    • Leucovorin Calcium oral tablet, Leading, 5 mg, bottle, 100 count, NDC 69315-0184-01
    • Leucovorin Calcium oral tablet, Teva, 25 mg, bottle, 25 count, NDC 00555-0485-27
    • Leucovorin Calcium oral tablet, Teva, 5 mg, bottle, 30 count, NDC 00555-0484-01
    • Leucovorin Calcium oral tablet, Teva, 5 mg, bottle, 100 count, NDC 00555-0484-02

Reason for the Shortage

    • Epic Pharma has leucovorin tablets available.
    • Hikma did not provide a reason for the shortage.
    • Ingenus did not provide a reason for the shortage.
    • Leading did not provide a reason for the shortage.
    • Teva did not provide a reason for the shortage.

Available Products

    • Leucovorin Calcium oral tablet, Epic Pharma, 10 mg, bottle, 12 count, NDC 42806-0133-21
    • Leucovorin Calcium oral tablet, Epic Pharma, 10 mg, bottle, 24 count, NDC 42806-0133-24
    • Leucovorin Calcium oral tablet, Epic Pharma, 15 mg, bottle, 24 count, NDC 42806-0134-24
    • Leucovorin Calcium oral tablet, Epic Pharma, 25 mg, bottle, 25 count, NDC 42806-0359-25
    • Leucovorin Calcium oral tablet, Epic Pharma, 5 mg, bottle, 30 count, NDC 42806-0358-30
    • Leucovorin Calcium oral tablet, Epic Pharma, 5 mg, bottle, 100 count, NDC 42806-0358-01

Estimated Resupply Dates

    • Hikma has all leucovorin tablets on back order and the company cannot estimate a release date. Short-dated product is available.
    • Ingenus has leucovorin tablets on allocation.
    • Leading has leucovorin 5 mg tablets in 30 count on allocation. All other presentations are on back order and the company estimates a release date of mid- to late-November 2025.
    • Teva has leucovorin 5 mg tablets in 30 count and 100 count bottles and 25 mg tablets in 25 count bottles on back order and the company estimates a release date in mid- to late-November 2025.

Updated

Updated November 13, 2025 by Leslie Jensen, PharmD, Drug Information Specialist. Created November 11, 2025 by Leslie Jensen, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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