11/9/2026

Melphalan Injection

Products Affected - Description

- Melphalan powder for solution for injection, Avenacy, 50 mg, vial, 1 count, NDC 83634-0202-61
- Melphalan powder for solution for injection, Avet Pharmaceuticals, 50 mg, vial, 1 count, NDC 23155-0355-41
- Melphalan powder for solution for injection, Dr. Reddy's, 50 mg, vial, 1 count, NDC 43598-0392-48
- Melphalan powder for solution for injection, Mylan Institutional (Viatris), 50 mg, vial, 1 count, NDC 67457-0195-01
- Melphalan powder for solution for injection, Teva, 50 mg, vial, 1 count, NDC 45963-0686-02

Reason for the Shortage

- Acrotech has Evomela available.
- Apotex has Ivra 90 mg/mL solution for injection available.
- Avenacy did not provide a reason for the shortage.
- Avet did not provide a reason for the shortage.
- Dr. Reddy's did not provide a reason for the shortage.
- Fosun has melphalan injection available.
- Fresenius Kabi discontinued melphalan injection in September 2026.
- Meitheal has melphalan injection available.
- Sagent has melphalan injection available.
- Teva did not provide a reason for melphalan injection.
- Viatris did not provide a reason for melphalan injection.

Available Products

- Evomela powder for solution for injection, Acrotech, 50 mg, vial, 1 count, NDC 72893-0001-01
- Ivra solution for injection, Apotex, 90 mg/mL, vial, 1 count, NDC 60505-6414-01
- Melphalan powder for solution for injection, Fosun Pharma, 50 mg, vial, 1 count, NDC 72266-0128-01
- Melphalan powder for solution for injection, Meitheal Pharmaceuticals, 50 mg, vial, 1 count, NDC 71288-0132-90
- Melphalan powder for solution for injection, Sagent, 50 mg, vial, 1 count, NDC 25021-0258-61

Estimated Resupply Dates

- Avenacy has melphalan 50 mg vials on back order and the company cannot estimate a release date.
- Avet has melphalan 50 mg vials on back order and the company estimates a release date of November 2026.
- Dr. Reddy's has melphalan 50 mg vials on back order and the company estimates a release date of early-January 2027.
- Teva has temporarily discontinued melphalan 50 mg vials.
- Viatris has melphalan 50 mg vials on back order and the company estimates a release date of mid- to late-November 2026.

Updated

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