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4/8/2025

Heparin Injection

Products Affected - Description

    • Heparin Sodium solution for injection, BBraun, 10,000 unit/mL, 0.5 mL prefilled syringe, 10 count, NDC 00264-5705-10 - discontinued
    • Heparin Sodium solution for injection, Hikma, 1,000 unit/mL, 30 mL multiple dose vial, 25 count, NDC 00641-2450-55
    • Heparin Sodium solution for injection, Hikma, 5,000 unit/mL, 0.5 mL preservative-free vial, 10 count, NDC 00641-6204-10
    • Heparin Sodium solution for injection, Hikma, 5,000 unit/mL, 1 mL syringe, 10 count, NDC 00641-6199-10
    • Heparin Sodium solution for injection, Hikma, 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 00641-2460-55
    • Heparin Sodium solution for injection, Mylan (Viatris), 20,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 67457-0373-99 - discontinued
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 00069-0058-01
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 30 mL multiple dose vial, 10 count, NDC 00069-0137-03
    • Heparin Sodium solution for injection, Pfizer, 5,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 00069-0059-03
    • Heparin Sodium solution for injection, Pfizer, 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 00069-0059-01
    • Heparin Sodium solution for injection, Pfizer, 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 00409-2723-02
    • Heparin Sodium solution for injection, Pfizer, 5,000 unit/mL, 1mL Carpuject syringe, 50 count, NDC 00409-1402-12
    • Heparin Sodium solution for injection, Sky, 1,000 unit/mL, 1 mL vial, 25 count, NDC 63739-0920-25 - discontinued
    • Heparin Sodium solution for injection, Sky, 1,000 unit/mL, 10 mL vial, 25 count, NDC 63739-0931-28 - discontinued
    • Heparin Sodium solution for injection, Sky, 10,000 unit/mL, 1 mL vial, 25 count, NDC 63739-0964-25 - discontinued
    • Heparin Sodium solution for injection, Sky, 20,000 unit/mL, 1 mL vial, 25 count, NDC 63739-0986-25 - discontinued
    • Heparin Sodium solution for injection, Sky, 5,000 unit/mL, 1 mL vial, 25 count, NDC 63739-0953-25 - discontinued
    • Heparin Sodium solution for injection, Sky, 5,000 unit/mL, 10 mL vial, 25 count, NDC 63739-0901-28 - discontinued

Reason for the Shortage

    • BBraun has discontinued heparin 10,000 unit/mL 0.5 mL prefilled syringes.
    • Fresenius Kabi has heparin injection available.
    • Hikma did not provide a reason for the shortage.
    • Meitheal Pharma has heparin injection available.
    • Mylan (Viatris) discontinued heparin 20,000 unit/mL 1 mL vials in March 2025.
    • Pfizer has heparin injection on shortage due to increased demand and manufacturing delays.
    • Sagent has heparin injection on shortage due to increased demand and manufacturing delays.
    • Sky discontinued heparin injection.
    • Techdow USA has heparin injection available.

Available Products

    • Heparin Sodium solution for injection, Fresenius Kabi, 1,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 63323-0540-13
    • Heparin Sodium solution for injection, Fresenius Kabi, 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 63323-0540-11
    • Heparin Sodium solution for injection, Fresenius Kabi, 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 63323-0540-15
    • Heparin Sodium solution for injection, Fresenius Kabi, 1,000 unit/mL, 2 mL single dose vial, 25 count, NDC 63323-0276-02
    • Heparin Sodium solution for injection, Fresenius Kabi, 1,000 unit/mL, 30 mL multiple dose vial, 25 count, NDC 63323-0540-31
    • Heparin Sodium solution for injection, Fresenius Kabi, 10,000 unit/mL, 0.5 mL preservative-free vial, 25 count, NDC 63323-0543-02
    • Heparin Sodium solution for injection, Fresenius Kabi, 10,000 unit/mL, 0.5 mL preservative-free vial, 25 count, NDC 63323-0543-13
    • Heparin Sodium solution for injection, Fresenius Kabi, 10,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 63323-0542-13
    • Heparin Sodium solution for injection, Fresenius Kabi, 10,000 unit/mL, 4 mL multiple dose vial, 25 count, NDC 63323-0459-09
    • Heparin Sodium solution for injection, Fresenius Kabi, 10,000 unit/mL, 5 mL multiple dose vial, 25 count, NDC 63323-0542-14
    • Heparin Sodium solution for injection, Fresenius Kabi, 20,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 63323-0915-01
    • Heparin Sodium solution for injection, Fresenius Kabi, 20,000 unit/mL, 1 mL glass multiple dose vial, 25 count, NDC 63323-0915-13
    • Heparin Sodium solution for injection, Fresenius Kabi, 5,000 unit/mL, 0.5 mL prefilled syringe, 24 count, NDC 63323-0118-05
    • Heparin Sodium solution for injection, Fresenius Kabi, 5,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 63323-0262-06
    • Heparin Sodium solution for injection, Fresenius Kabi, 5,000 unit/mL, 1 mL prefilled syringe, 24 count, NDC 76045-0108-10
    • Heparin Sodium solution for injection, Fresenius Kabi, 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 63323-0047-10
    • Heparin Sodium solution for injection, Hikma, 1,000 unit/mL, 1 mL single dose vial, 25 count, NDC 00641-0391-12
    • Heparin Sodium solution for injection, Hikma, 10,000 unit/mL, 1 mL single dose vial, 25 count, NDC 00641-0410-12
    • Heparin Sodium solution for injection, Hikma, 5,000 unit/mL, 1 mL single dose vial, 25 count, NDC 00641-0400-12
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 unit/mL, 1 mL vial, 25 count, NDC 71288-0402-02
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 unit/mL, 10 mL vial, 25 count, NDC 71288-0402-11
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 unit/mL, 10 mL vial, NDC 71288-0402-10
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 unit/mL, 30 mL vial, 25 count, NDC 71288-0402-31
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 unit/mL, 30 mL vial, NDC 71288-0402-30
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 1,000 units/mL, 2 mL vial, 25 count, NDC 71288-0400-03
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 10,000 unit/mL, 1 mL vial, 25 count, NDC 71288-0404-02
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 10,000 unit/mL, 1 mL vial, NDC 71288-0404-01
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 10,000 unit/mL, 4 mL vial, 25 count, NDC 71288-0404-05
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 10,000 unit/mL, 4 mL vial, NDC 71288-0404-04
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 5,000 unit/mL, 1 mL vial, 25 count, NDC 71288-0403-02
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 5,000 unit/mL, 10 mL vial, 25 count, NDC 71288-0403-11
    • Heparin Sodium solution for injection, Meitheal Pharmaceuticals, 5,000 unit/mL, 10 mL vial, NDC 71288-0403-10
    • Heparin Sodium solution for injection, Mylan (Viatris), 1,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 67457-0372-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 67457-0385-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 1,000 unit/mL, 30 mL multiple dose vial, 25 count, NDC 67457-0384-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 10,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 67457-0602-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 10,000 unit/mL, 4 mL multiple dose vial, 25 count, NDC 67457-0603-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 5,000 unit/mL, 1 mL multiple dose vial, 25 count, NDC 67457-0374-99
    • Heparin Sodium solution for injection, Mylan (Viatris), 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 67457-0383-99
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 1 mL single dose vial, 25 count, NDC 00409-2720-01
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 00409-2720-02
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 2 mL preservative-free vial, 25 count, NDC 00069-0043-01
    • Heparin Sodium solution for injection, Pfizer, 1,000 unit/mL, 30 mL multiple dose vial, 25 count, NDC 00409-2720-03
    • Heparin Sodium solution for injection, Pfizer, 10,000 unit/mL, 0.5 mL preservative-free Carpuject syringe, 50 count, NDC 00409-1316-32
    • Heparin Sodium solution for injection, Pfizer, 10,000 unit/mL, 1mL single dose vial, 25 count, NDC 00409-2721-01
    • Heparin Sodium solution for injection, Pfizer, 5,000 unit/mL, 1mL single dose vial, 25 count, NDC 00409-2723-01
    • Heparin Sodium solution for injection, Sagent, 1,000 unit/mL, 1 mL vial, 25 count, NDC 25021-0400-01
    • Heparin Sodium solution for injection, Sagent, 1,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 25021-0400-10
    • Heparin Sodium solution for injection, Sagent, 1,000 unit/mL, 2 mL single dose vial, 25 count, NDC 25021-0401-02
    • Heparin Sodium solution for injection, Sagent, 1,000 unit/mL, 30 mL multiple dose vial, 25 count, NDC 25021-0400-30
    • Heparin Sodium solution for injection, Sagent, 10,000 unit/mL, 1 mL vial, 25 count, NDC 25021-0403-01
    • Heparin Sodium solution for injection, Sagent, 10,000 unit/mL, 4 mL multiple dose vial, 25 count, NDC 25021-0403-04
    • Heparin Sodium solution for injection, Sagent, 20,000 unit/mL, 1mL multiple dose vial, 25 count, NDC 25021-0404-01
    • Heparin Sodium solution for injection, Sagent, 5,000 unit/mL, 1 mL vial, 25 count, NDC 25021-0402-01
    • Heparin Sodium solution for injection, Sagent, 5,000 unit/mL, 10 mL multiple dose vial, 25 count, NDC 25021-0402-10
    • Heparin Sodium solution for injection, Techdow USA, 1,000 unit/mL, 1 mL vial, 25 count, NDC 81952-0112-06
    • Heparin Sodium solution for injection, Techdow USA, 1,000 unit/mL, 10 mL vial, 25 count, NDC 81952-0112-09
    • Heparin Sodium solution for injection, Techdow USA, 1,000 unit/mL, 2 mL vial, 25 count, NDC 81952-0115-07
    • Heparin Sodium solution for injection, Techdow USA, 1,000 unit/mL, 30 mL vial, 25 count, NDC 81952-0112-10
    • Heparin Sodium solution for injection, Techdow USA, 10,000 unit/mL, 1 mL vial, 25 count, NDC 81952-0113-06
    • Heparin Sodium solution for injection, Techdow USA, 10,000 unit/mL, 5 mL vial, 25 count, NDC 81952-0113-08
    • Heparin Sodium solution for injection, Techdow USA, 20,000 unit/mL, 1 mL vial, 25 count, NDC 81952-0116-06
    • Heparin Sodium solution for injection, Techdow USA, 5,000 unit/mL, 1 mL vial, 25 count, NDC 81952-0111-06

Estimated Resupply Dates

    • Hikma has heparin 1,000 unit/mL 30 mL vials on intermittent back order and the company is releasing supplies as they become available. The 5,000 unit/mL 1 mL syringes are on allocation. Short-dated product is available with an expiration date of April 2025. The 5,000 unit/0.5 mL preservative free vials and 5,000 unit/mL 10 mL vials are on back order and the company cannot estimate a release date.
    • Pfizer has heparin 5,000 unit/mL 1 mL carpuject syringes and 5,000 unit/mL 10 mL vials are available in limited supply (short-dated product is available). Pfizer has temporarily discontinued heparin 1,000 unit/mL 10 mL vials, 1,000 unit/mL 30 mL vials, 5,000 unit/mL 1 mL vials, and 5,000 unit/mL 10 mL vials.

Updated

Updated April 8, 2025 by Leslie Jensen, PharmD, Drug Information Specialist. Created October 13, 2017 by Leslie Jensen, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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