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8/14/2026

Calcitriol Oral Solution

Products Affected - Description

    • Calcitriol oral solution, Sun Pharma, 1 mcg/mL, 15 mL bottle, NDC 63304-0241-59 - discontinued

Reason for the Shortage

    • Hikma has calcitriol oral solution available.
    • Rising has calcitriol oral solution available.
    • Sun Pharma discontinued calcitriol oral solution.

Available Products

    • Calcitriol oral solution, Hikma, 1 mcg/mL, 15 mL bottle, NDC 00054-3120-41
    • Calcitriol oral solution, Rising Pharmaceuticals, 1 mcg/mL, 15 mL bottle, NDC 64980-0447-15

Estimated Resupply Dates

    • All marketed presentations are available.

Implications for Patient Care

    • Calcitriol is commonly used for the treatment of secondary hyperparathyroidism and metabolic bone disease in chronic kidney disease patients both on and off chronic hemodialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.[1]

Safety

    • Dosing is expressed in micrograms (mcg; not milligrams (mg))[1]
    • Unit conversion for Vitamin D: 1 international unit (IU) = 0.025 mcg[2]

Alternative Agents & Management

    • KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD): https://kdigo.org/wp-content/uploads/2026/04/KDIGO-2017-CKD-MBD-Guideline.pdf
    Table -
    Drug NameVitamin D Form, Active/InactiveDosage Forms and Strength
    Particalcitol3 D2, ActiveIntravenous Solution
    · 5 mcg/mL
    · 2 mcg/mL
    · 10 mcg/mL
    Oral Capsule
    · 1 mcg
    · 2 mcg
    · 4 mcg
    Ergocalciferol4 D2, InactiveOral Capsule
    · 1,250 mcg (50,000 IU)
    Oral Solution
    · 200 mcg/mL
    Doxercalciferol5 D2, InactiveIntravenous Solution
    · 2 mcg/mL
    Oral Capsule
    · 0.5 mcg
    · 1 mcg
    · 2.5 mcg
    Calcitriol1 D3, ActiveIntravenous Solution
    · 1 mcg/mL
    · 2 mcg/mL
    Oral Solution
    · 1 mcg/mL
    Oral Capsule
    · 0.25 mcg
    · 0.5 mcg
    Cholecalciferol6 D3, InactiveOral Tablet
    Oral Capsule
    Oral Solution

    Various Strengths
    Calcifediol7 D3, InactiveOral Capsule
    · 30 mcg

References

    1. Calcitriol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.
    2. Unit Conversions. Dietary Supplement Ingredient Database. Updated January 1, 2026. Accessed July 1, 2026. https://dsid.od.nih.gov/unit-conversions.
    3. Paricalcitol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.
    4. Ergocalciferol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.
    5. Doxercalciferol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.
    6. Cholecalciferol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.
    7. Calcifediol. Lexicomp Online. Wolters Kluwer Clinical Drug Information. Hudson, Ohio, USA. Accessed July 1, 2026.

Updated

Updated August 14, 2026 by Michelle Wheeler, PharmD, Drug Information Specialist. Created February 24, 2023 by Leslie Jensen, PharmD, Drug Information Specialist. © 2026, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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