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12/22/2025

Insulin Human Regular Concentrated

Products Affected - Description

    • Humulin R solution for injection, Lilly USA, LLC, 500 unit/mL, 20 mL multiple dose vial, NDC 00002-8501-01 - discontinued

Reason for the Shortage

    • Lilly discontinued Humulin-R U-500 vials in late-2025.

Available Products

    • Humulin R solution for injection, Lilly USA, LLC, 500 unit/mL, 3 mL KwikPen pen, 2 count, NDC 00002-8824-27

Estimated Resupply Dates

    • Lilly has Humulin-R 500 units/mL 3 mL KwikPens available.

Updated

Created December 22, 2025 by Michelle Wheeler, PharmD, Drug Information Specialist. © 2025, Drug Information Service, University of Utah, Salt Lake City, UT.

Disclaimer

Drug Shortage Bulletins are copyrighted by the Drug Information Service of the University of Utah and provided by ASHP as its exclusive authorized distributor. ASHP and the University of Utah make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information, and specifically disclaim all such warranties. Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use.

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